European suspension of AstraZeneca vaccine WILL cause Covid deaths, experts warn

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Europe’s medical watchdog today slapped down Germany for suspending AstraZeneca’s coronavirus vaccine over blood clot fears.

The European Medicines Agency (EMA) said there was ‘no evidence’ to support halting the jab for people under 60, adding that the benefits of protecting against Covid far outweighed the risk of the extremely rare brain clots. 

The regulator found just 44 out of 9.1million people vaccinated with the British-made jab on the continent have developed the condition, known as cerebral sinus venous thrombosis — a rate of about five per million.

Emer Cooke, the EMA’s executive director, told a press conference this afternoon there was still no proof the vaccine had caused CSVT and admitted those people might have developed the condition anyway. 

She said: ‘At present, the experts have advised us that they have not been able to identify specific risk factors, including age, gender or previous medical history of clotting disorders, for these very rare events.

‘And, as I mentioned previously, a causal link of the vaccine has not yet been proven but it is possible, and further analysis is still ongoing. According to the current scientific knowledge, there is no evidence to support restricting the use of this vaccine in any population.’

The EMA’s ruling puts the watchdog at odds with many EU member states which have restricted the jab’s rollout in certain age groups amid the clotting fears.

Germany last night became the latest country to halt the vaccine in the age group after 31 out of 2.7million Germans given the AZ jab developed the condition. 

There have been dozens of reports of inoculated people, predominantly women under 55, suffering brain clots after getting the jab.

But the EMA, which is carrying out a major review into the link between the jab and rare condition, said it could not find any common links between the patients.

As well as age, the regulator ruled out gender, other illnesses or a history of clotting as risk factors for the brain clot, known as cerebral sinus venous thrombosis.

British scientists today warned that Europe’s suspension of the AstraZeneca vaccine will erode public confidence in the jab and cause more coronavirus deaths. 

Dr Simon Clarke, a microbiologist at the University of Reading, told MailOnline it ‘seems likely’ there will be some ‘avoidable deaths’ in the UK  because fewer people will come forward for their appointment.

His comments were echoed by Dr Peter English, a former British Medical Association chief, who slammed EU nations for stoking fears about the vaccine.

He said there was ‘no evidence’ vaccination was behind the clotting, adding: ‘Any decision to withhold the vaccine will directly cause excess, avoidable Covid deaths.’ 

Meanwhile, Communities Secretary Robert Jenrick today pleaded with Brits to keep their faith in the AZ jab, pointing out that ‘study after study’ had shown it was safe.  

When concerns were first raised about the vaccine’s link to clots earlier this month, GPs in England warned as many as one in 10 patients were either not showing up, asking to cancel or double-checking which jab they were getting before attending their appointment. 

There are fears the problem will become more widespread as countries on the continent continue to revolt against the jab. 

The EU is currently battling a third Covid wave which has sent several countries back into national lockdowns and is struggling to get its vaccination programme up to speed. 

Yet several member states have paused rollouts of the AstraZeneca vaccine after a tiny number of inoculated people, predominantly women under 55, suffered deadly brain clots. 

The World Health Organization said today it continues to monitor the jab’s safety but the benefit-risk assessment ‘weighs heavily in favour of its use’. 

Alejandro Cravioto, chair of the WHO’s Strategic Advisory Group of Experts (SAGE) on Immunization, told a briefing the panel was ‘comfortable’ with the vaccine’s use, since many of the countries using it have safety warning signal systems in place and are not reporting problems.

Germany became the latest country to stop giving the jab to people under the age of 60, after the rare condition was spotted in 31 out of 2.7million vaccinated people — a rate of around one in 90,000.

France and Norway are not allowing under-55s to get AstraZeneca’s vaccine, while Spain has banned its use in under-65s.

AstraZeneca still maintains the clots are not occurring any more frequently than they would in the general population, a claim which has been echoed repeatedly by medical regulators in the UK and EU.

When asked about the effect of the EU’s suspensions on Britain’s vaccine rollout, Dr Clarke told MailOnline: ‘I think it’s fair to say any anti-vaccine worries people here have could be bolstered by attitudes of some European regulators and governments. 

‘That could lead to avoidable deaths if, as seems likely, that means they don’t get vaccinated.’

It comes after German health minister Jens Spahn and state officials agreed unanimously last night to only give the vaccine to people aged 60 or older, unless they belonged to a high-risk category for serious illness from Covid and had agreed with their doctor to take the vaccine.

Earlier in the week Canada also halted its use in people under the age of 55 over the same clotting fears. 

The European Medicines Agency (EMA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA) both concluded that the benefits of the vaccine far outweighed the risks.  

Dr English, former chair of the BMA’s Public Health Medicine Committee, said there was no proof the vaccine was linked to the clotting, or that prevalence was more common in inoculated groups than in the general population.

He added: ‘There is no evidence that these cases are caused by vaccination, rather than simply associated with it, in people who would have had such conditions anyway.

‘Right now, in the middle of a pandemic, with case numbers rising alarmingly, any risk from vaccination has to be set against the risk of disease. 

‘A decision may be thought of as ‘precautionary’; but if people are not vaccinated, because use of the vaccine is suspended, or because of a drop in confidence in the vaccine caused by the decision, some of them will get ill from Covid-19; and some of them will die. Any decision to withhold the vaccine will directly cause excess, avoidable Covid-19 deaths.’ 

Communities secretary Robert Jenrick said today he was ‘100 per cent confident’ in the AZ jab, adding that ‘study after study’ had shown it is safe and is saving thousands of lives. 

He told Sky News: ‘People should continue to go forward, get the vaccine, I certainly will when my time comes, it is a safe vaccine and the UK’s vaccine rollout is saving people’s lives right across the country every day.’ 

A review by Germany’s medical regulator  found a total of 31 unusual blood clots, including nine deaths, were reported by March 29 out of some 2.7million doses of AstraZeneca administered in Germany. 

Twenty-nine of the cases were in women aged 20 to 63 and two in men aged 39 and 56. 

In a statement, AstraZeneca said that tens of millions of people worldwide have received its vaccines and noted the European Medicines Agency’s conclusion that the benefits of the shot outweigh the risks.

The company said it would continue to work with German authorities to address any questions they might have, while also analysing its own records to understand whether the rare blood clots reported occur more commonly ‘than would be expected naturally in a population of millions of people’.

Scientists insist the risk of blood clots is no higher than in the general population.  

The 31 clots spotted by German officials are cases of cerebral sinus venous thrombosis (CSVT).

CSVT is a rare clot in a vein draining blood from the brain that, left untreated, can cause a life-threatening brain haemorrhage or stroke. 

It was this condition that panicked European drug regulators earlier in March but the European Medicines Agency found no proof the jab was causing it. Scientists and politicians slammed Germany’s move as a backwards step going over old ground.

Most of the cases were in younger women but the AstraZeneca vaccinations have been stopped for both men and women. People can still get the Pfizer and Moderna jabs that are being used on the continent. 

Dr Clarke told MailOnline: ‘Whenever you do these things you need to have a reason to do them. It’s all a balance of risk. 

‘There is no evidence that there is a problem but, even if there was, then you’re reducing what, at worst, is a tiny risk and imposing a bigger one by not giving people the protection of a vaccine.

‘People still get on airplanes and we know that there is a real risk of blood clotting if you’re sat on a plane for hours, but people still do it because they want to go on holiday.

‘So if people are more concerned about blood clots than they are Covid, I’d say they have their priorities all wrong.

‘You have to wonder what the thinking is. Are they being entirely up front? Because it just doesn’t make sense as it is presented. Maybe they know something they’re not letting on.’              

Berlin’s health minister, Dilek Kalayci, said ‘everyone who has already received a first jab of AstraZeneca has very good protection’ but that there were new worries about possible side effects.

As a result, all upcoming appointments for the vaccine would be cancelled in Berlin for the coming days. 

MPs in the UK said the move was ‘ludicrous’ and a repeat of what happened earlier in the month, which later turned out to be baseless.

Senior Tory backbencher Peter Bone said the decision to ban the drug ‘reeks of total confusion within the European Union’.

‘One thing is for sure, while the majority of our adult population has had its first jabs only a fraction in Europe have,’ he said.

‘None of it makes any logical sense, they seem to be in total confusion. The medical advice is that it does a great job.’

He added: ‘My constituents are very happy to have it and if the Germans don’t want it, send it over to us, we will use it, no problem.’

Another Tory MP said: ‘This is ludicrous. The WHO has said it is perfectly safe. The EMA has said it is safe. Our regulator has said it is safe.

‘It does look very much like a vendetta that the EU is maintaining both against AstraZeneca, because they are adhering to their contract, and the UK, out of spite.’